congenital defect

Neural tube defects (NTDs) are the most common defects of the central nervous system, with a strong impact on infant morbidity and mortality.
These are some of the milestones that can be highlighted about their evolution:
- 70s: advances in medical/surgical therapies lead to a significant reduction of sequelae and disability.

According to the World Health Organization (WHO), every year, about 8 million children are born with a birth defect in the world. Congenital anomalies cause 10 per cent of all newborn deaths and many of the babies who survive are at risk of carrying a lifelong disability if they do not have timely access to high-quality care.

However, the burden of death and disability differs by place of birth and is disproportionately high in low- and middle-income countries.